99%+ Dapoxetine Hydrochloride Powder
Product Name: Dapoxetine hydrochloride
Alias: Priligy, Dapoxe, Dapoxeti , Dapoxetinehy, Dapoxetine HCl
CAS No: 129938-20-1 or 119356-77-3
Appearance: White crystalline powder
Dapoxetine, marketed as Priligy (among and also other brands) could be the first compound developed specially for your treatments for premature ejaculation (PE) for males between 18-64 years of age. Dapoxetine functions inhibiting the serotonin transporter, increasing serotonin is action on the post synaptic cleft, in order to delay consequence ejaculation. As being a part of selective serotonin reuptake inhibitor (SSRI) family, Dapoxetine was first created being an antidepressant. However, unlike other SSRIs, Dapoxetine is absorbed and eliminated rapidly in your body. Its immediate response makes it suitable for treating PE however, not as an antidepressant.
Dapoxetine hydrochloride, a fast-acting serotonin reuptake transporter inhibitor, is generally prescribed for your treatment and control over premature ejaculation and male impotence in adult male.Due to deficiency of specific approval treatment for PE in america and a few other countries, other SSRIs including Fluoxetine, Paroxetine, Sertraline, Fluvoxamine, and Citalopram have already been used as clinical drugs to deal with PE. Waldinger?¡¥s meta analysis implies that the usage of these conventional antidepressants increasing IELT about 2-9 time in comparison of three to eight instances when Dapoxetine can be used. However, these SSRIs must be taken daily in order to achieve meaningful efficacy, and also the long half-life increases the risk of the drug accumulation and as a consequence, a growing uncomfortable side effects like decreasing sexual libido and causing male impotence. Dapoxetine, on the other hand, can be a fast-acting SSRI. It’s rapidly absorbed and eliminated from the body in a several hours. This favorable pharmacokinetics minimizes the risk of the drug?¡¥s accumulation in the body, and for that reason reducing unwanted effects.
Dapoxetine hydrochloride is often a selective serotonin reuptake inhibitor. The physiology of ejaculation primarily depends upon serotonin and dopamine receptors including 5-HT1a and 5-HT2c. Dapoxetine hydrochloride prevents the reuptake of serotonin transporter. The drug binds with all the reuptake transporters of norepinephrine and dopamine and inhibits the reuptake.
For premature ejaculation and erectile dysfunctions (Adults):The recommended adult dose of Dapoxetine hydrochloride is 30 – 60 mg/day. The utmost dose ought not exceed 100 mg/day. Take Dapoxetine hydrochloride no less than two hours before sexual intercourse to attain maximum treatment benefits.