Cardarine/GW501516 Powder

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Purity Cardarine/GW501516 Powder For Sale:
Minimum Order Quantity: 10g
Synonym: 2-[2-methyl-4-[[4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl]methylsulfanyl]phenoxy]acetic acid; Endurobol
Application: A selective and potent PPARβ agonist
CAS Number: 317318-70-0
Purity: ≥97%
Molecular Weight: 453.50
Molecular Formula: C21H18F3NO3S2
Physical State: Solid
Solubility: Soluble in water (slightly), DMSO (50 mg/ml), DMF (25 mg/ml), 100% ethanol (<1mmol)), and methanol (50 mg/ml).
Storage: Store at 4° C
Melting Point: 134-136° C
Boiling Point: ~584.5° C at 760 mmHg (Predicted)

GW-501516 powder Description:
GW501516 is the most selective and potent PPARβ (EC50=1.1nM) agonist that has been demonstrated to be 1,000-fold more selective in comparison to existing subtypes. Studies demonstrate that GW501516 can regulate expression of genes involved in lipid catabolism and energy uncoupling in skeletal muscle cells. Additionally, GW501516 has been shown to block insulin resistance and fatty acid-induced nuclear factor-κB (NF-κB) activation.

GW-501516 powder Applications:

Cardarine (GW-501516) binds to the PPAR receptor, specifically a group of nuclear receptors (sensors that detect thyroid and steroidal hormones in the body) that initiates the PGC-1a enzyme. This action leads to gene expression, specifically genes that revolve around energy expenditure.

Studies involving GW-501516 have shown to increase the metabolism of fatty acids in rats. It was also shown in the same studies to reduce the odds of obesity despite poor eating habits as well as prevent Type-2 diabetes. Cardarine was also shown to increase HDL (good cholesterol) and decrease LDL (bad cholesterol) in a study using monkeys. The effects seemed to hold true with or without exercise.

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